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Q.106 Botany ⭐ 360° Option Elimination Active
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NEET 2025 Botany Question 106 Solution

Topic: Molecular Basis of Inheritance · Official NTA Booklet Code 45
NEET 2025 Botany Question 106: Salient Features of the Human Genome

Question

Which chromosome in the human genome has the highest number of genes?

✓
Verified Against NTA Final Answer Key
Option (3) : Chromosome 1
📚 Molecular Basis of Inheritance Easy
📋 Given Parameters & Problem Setup
Organism Homo sapiens (Human genome)
Target Feature Chromosome with highest gene count
⚡

The 30-Second Exam Hall Shortcut: ⚡ HGP Extremes Fingerprint

⏱️ Save ~25 seconds

Chromosome 1 is the BIGGEST with the MOST genes (2,968 genes)! Chromosome Y is the SMALLEST with FEWEST genes (231 genes)!

1 Recall the salient features of the Human Genome Project (HGP):
2 - Total genes estimated: ~30,000.
3 - Chromosome 1 has the most genes: 2,968 genes.
4 - Chromosome Y has the fewest genes: 231 genes.
5 - Average gene size: 3000 bases (largest human gene is dystrophin at 2.4 million bases).
6 Highest gene count = Chromosome 1!
7 Select Option (3) immediately!
🛡️
Why You Can 100% Trust This Shortcut: Human Genome Project Salient Findings (NCERT Biology · Molecular Basis of Inheritance: Chromosome 1 has 2968 genes, Y has 231).
📐

Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Core Findings of the Human Genome Project (HGP)

The complete sequencing of the human genome revealed extraordinary insights into the genetic architecture of humans:

  • • The human genome contains 3164.7 million nucleotide base pairs (3.164 Gb).
  • • The total number of genes is estimated at 30,000, much lower than previous estimates of 80,000 to 140,000 genes.
  • • Almost all (99.9%) nucleotide bases are exactly the same in all people.
Step 2

Distribution of Genes Across Human Chromosomes

Genes are not evenly distributed across human chromosomes:

  • • Chromosome 1 (the largest human autosome) contains the highest number of genes: exactly 2,968 genes.
  • • Chromosome 1 was the last chromosome to be completely sequenced (completed in May 2006).
  • • Chromosome Y contains the fewest genes: only 231 genes.
Step 3

Conclusion

Chromosome 1 holds the record for harboring the highest number of annotated protein-coding genes in the human genome.

Max Genes=Chromosome 1 (2,968 genes)\text{Max Genes} = \text{Chromosome 1 (2,968 genes)}
⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan
1 A
✗ Incorrect
Verdict & Scientific Reason:

Incorrect. Chromosome X contains approximately 800–900 genes, far fewer than Chromosome 1.

⚠️
Student Fallacy (Why candidates pick this trap): Assuming the sex chromosome X has the most genes due to its high frequency in sex-linked inheritance questions.
2 B
✗ Incorrect
Verdict & Scientific Reason:

Incorrect. Chromosome Y has the FEWEST genes in the entire human genome (only 231 genes).

⚠️
Student Fallacy (Why candidates pick this trap): Confusing highest with lowest extremes.
3 C
✓ 100% Correct
Verdict & Scientific Reason:

100% correct. Chromosome 1 contains 2,968 genes, the maximum among all human chromosomes.

💡
Why this is airtight: None; direct NCERT factual recall.
4 D
✗ Incorrect
Verdict & Scientific Reason:

Incorrect. Chromosome 10 contains roughly 700–800 genes, well below Chromosome 1.

⚠️
Student Fallacy (Why candidates pick this trap): Random guessing.
⚠️

NTA Trap Alert: Confusing Chromosome 1 (Most Genes) with Chromosome Y (Fewest Genes)

NCERT highlights both extremes together: Chromosome 1 has 2968 genes, while Chromosome Y has 231 genes. Always check whether the question asks for highest or lowest!

🛡️ How to avoid the -1 mark: Remember: #1 is first and biggest (2968 genes); Y is tiny and has the fewest (231 genes).
📖

Core NEET Syllabus Standard

NEET Biology Core Syllabus · Molecular Basis of Inheritance Standard Benchmark
Core Scientific Principle Tested:

"Chromosome 1 has the most genes (2968), and the Y chromosome has the fewest (231)."

Syllabus Focus: Human Genome Project · Salient Features
✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗
Number #1 is FIRST and has the MOST (2,968 genes)!

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⚖️ Legal & Fair Dealing Notice: Sourced from publicly released NEET 2025 question papers and NEET answer keys for private study, research, and non-commercial educational practice under Fair Dealing (Section 52(1)(a) of the Indian Copyright Act, 1957). Not affiliated with or endorsed by NTA or NMC.

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