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Match List I with List II. List I: A. α-1 antitrypsin; B. Cry IAb; C. Cry IAc; D. Enzyme replacement therapy. List II: I. Cotton bollworm; II. ADA deficiency; III. Emphysema; IV. Corn borer. Choose the correct answer from the options given below:
α-1 antitrypsin = Emphysema (III); Cry IAb = Corn borer (IV); Cry IAc = Cotton bollworm (I); Enzyme replacement = ADA deficiency (II)! Match: A-III, B-IV, C-I, D-II!
Transgenic animals are produced to yield biological products; human protein (α-1-antitrypsin) is used to treat emphysema (A -> III). Adenosine deaminase (ADA) deficiency can be treated in some children by bone marrow transplantation or enzyme replacement therapy (in which functional ADA is given to the patient by injection) (D -> II).
The proteins encoded by genes cryIAc and cryIIAb control cotton bollworms (C -> I), while that encoded by cryIAb controls corn borer (B -> IV).
A-III, B-IV, C-I, D-II corresponds to Option (1).
Diagnose every choice: Know exactly why the right option works and why distractors fail.
Accurately pairs all four biological products and therapeutic strategies with their corresponding targets.
Mismatches α-1 antitrypsin with ADA deficiency.
Inverts Cry IAb and Cry IAc pest targets.
Mismatches Cry IAb with cotton bollworm.
Swapping cotton bollworm and corn borer.
"Human protein (alpha-1-antitrypsin) is used to treat emphysema. The proteins encoded by the genes cryIAc and cryIIAb control the cotton bollworms, that of cryIAb controls corn borer. ADA deficiency can be treated by enzyme replacement therapy."
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