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Q.192 Zoology ⭐ 360° Option Elimination Active
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NEET 2023 Zoology Question 192 Solution

Topic: Body Fluids and Circulation · Official NTA Booklet Code G5
NEET 2023 Zoology Question 192: Leukocyte Biology: Structure and Function of Basophils

Question

Which of the following statements are correct? A. Basophils are most abundant cells of the total WBCs B. Basophils secrete histamine, serotonin and heparin C. Basophils are involved in inflammatory response D. Basophils have kidney shaped nucleus E. Basophils are agranulocytes Choose the correct answer from the options given below:

  1. (1)A and B only
  2. (2)D and E only
  3. (3)C and E only
  4. (4)B and C only
✓
Verified Against NTA Final Answer Key
Option (4) : B and C only
📚 Body Fluids and Circulation Easy
📋 Given Parameters & Problem Setup
Cell Type Basophils (Granulocytic White Blood Cells)
Statements 5 statements (A-E) on abundance, secretions, inflammation, nucleus, and granule status
⚡

The 30-Second Exam Hall Shortcut: ⚡ Basophil Fact Checker: Least Abundant Granulocyte!

⏱️ Save ~25 seconds

Basophils are the LEAST abundant WBCs (0.5–1%, ruling out A). They are GRANULOCYTES (ruling out E) with S-shaped/bilobed nuclei (monocytes have kidney-shaped, ruling out D). They secrete histamine, serotonin, heparin (B) and mediate inflammation (C)! Match Option (4) B and C only!

1 Statement A: Basophils are most abundant -> False (Neutrophils are most abundant 60–65%; basophils are least abundant 0.5–1%).
2 Statement B: Secrete histamine, serotonin, heparin -> True.
3 Statement C: Involved in inflammatory responses -> True.
4 Statement D: Kidney-shaped nucleus -> False (Kidney-shaped is monocyte; basophil has S-shaped/irregular 2–3 lobed nucleus).
5 Statement E: Basophils are agranulocytes -> False (They are granulocytes).
6 B and C only -> Select Option (4).
🛡️
Why You Can 100% Trust This Shortcut: Canonical NCERT Human Physiology formed elements and leukocyte profiles.
📐

Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Evaluation of Statements B and C (Valid Statements)

Basophils are circulating granulocytes containing coarse basophilic granules (staining with basic dyes like methylene blue). Their granules release potent inflammatory vasoactive mediators:

Basophils⟶{Histamine(Vasodilator)Serotonin(Vasoconstrictor)Heparin(Anticoagulant)  ⟹  Mediate Inflammatory Responses\text{\textbf{Basophils}} \longrightarrow \begin{cases} \mathbf{\text{Histamine}} & (\text{Vasodilator}) \\[2pt] \mathbf{\text{Serotonin}} & (\text{Vasoconstrictor}) \\[2pt] \mathbf{\text{Heparin}} & (\text{Anticoagulant}) \end{cases} \implies \mathbf{\text{Mediate Inflammatory Responses}}
Step 2

Evaluation of Statements A, D, and E (Invalid Statements)

Analyzing the errors in the false statements: - Statement A: Neutrophils are the most abundant (60−65%60-65\%). Basophils are the least abundant (0.5−1%0.5-1\%). - Statement D: Monocytes have a characteristic large kidney-shaped/bean-shaped nucleus. Basophils have an S-shaped or bilobed nucleus obscured by dark granules. - Statement E: Granulocytes include neutrophils, eosinophils, and basophils. Agranulocytes include lymphocytes and monocytes.

Step 3

Verbatim NCERT Reference

NCERT states verbatim: "Basophils are least (0.5-1 per cent) among them. Basophils secrete histamine, serotonin, heparin, etc., and are involved in inflammatory reactions."

⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan
1 1
✗ Incorrect
Verdict & Scientific Reason:

Includes false statement A (basophils are the least, not most, abundant WBCs).

⚠️
Student Fallacy (Why candidates pick this trap): Confusing basophils with neutrophils in relative abundance.
2 2
✗ Incorrect
Verdict & Scientific Reason:

Both D (kidney-shaped nucleus describes monocytes) and E (basophils are granulocytes) are false.

⚠️
Student Fallacy (Why candidates pick this trap): Confusing agranulocyte morphology with basophils.
3 3
✗ Incorrect
Verdict & Scientific Reason:

Includes false statement E.

⚠️
Student Fallacy (Why candidates pick this trap): Calling basophils agranulocytes.
4 4
✓ 100% Correct
Verdict & Scientific Reason:

Statements B and C are completely accurate textbook facts regarding basophil physiology.

💡
Why this is airtight: None; textbook verbatim precision.
⚠️

NTA Trap Alert: Monocyte vs. Basophil Nucleus Morphology Trap

Monocytes have a kidney/bean-shaped nucleus. Eosinophils have a bilobed spectacle-shaped nucleus. Neutrophils have multi-lobed (3-5 lobes) nucleus. Basophils have an S-shaped/irregular nucleus.

🛡️ How to avoid the -1 mark: Kidney-shaped = Monocyte. S-shaped with dark granules = Basophil.
📖

Core NEET Syllabus Standard

NCERT Biology · Body Fluids and Circulation Standard Benchmark
Core Scientific Principle Tested:

"Basophils secrete histamine, serotonin, heparin, and are involved in inflammatory reactions. They are the least abundant granulocytes."

Syllabus Focus: Formed Elements (Leukocytes)
✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

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