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Which of the following stages of meiosis involves division of centromere?
In Meiosis I (Anaphase I), homologous chromosome pairs separate without centromere division! Centromeres split exclusively during Anaphase II, allowing sister chromatids to disjoin and migrate as individual chromosomes. Match Option (3)!
The behavior of centromeres is the single defining difference between meiotic stages:
Meiosis II closely resembles a standard mitotic division. At Anaphase II, the cohesin proteins at the centromeric region are cleaved, the centromere divides, and the kinetochore microtubules pull sister chromatids toward opposite spindle poles.
Diagnose every choice: Know exactly why the right option works and why distractors fail.
In Metaphase I, bivalents align on the double equatorial plate; no centromere division occurs.
In Metaphase II, chromosomes align individually on the equatorial plate; division takes place subsequently in anaphase.
The centromere of each chromosome divides simultaneously at Anaphase II, allowing sister chromatids to migrate to opposite poles.
In Telophase II, chromosomes decondense and nuclear envelopes reform around daughter nuclei.
Many candidates wrongly assume centromeres divide in both Anaphase I and Anaphase II. In Anaphase I, only whole dyad chromosomes separate; centromeres remain intact.
"Division of centromeres and separation of sister chromatids occurs during Anaphase II of meiosis."
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