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Q.55 Zoology ⭐ 360° Option Elimination Active
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NEET 2020 Zoology Question 55 Solution

Topic: Biotechnology and its Applications · Official NTA Booklet Code E1
NEET 2020 Zoology Question 55: Biotechnological Tools and Applications Match

Question

Match the following columns and select the correct option. Column - I Column - II (a) Bt cotton (i) Gene therapy (b) Adenosine (ii) Cellular defence deaminase deficiency (c) RNAi (iii) Detection of HIV infection (d) PCR (iv) Bacillus thuringiensis (a) (b) (c) (d)

  1. (1)(iv) (i) (ii) (iii)
  2. (2)(iii) (ii) (i) (iv)
  3. (3)(ii) (iii) (iv) (i)
  4. (4)(i) (ii) (iii) (iv)
✓
Verified Against NTA Final Answer Key
Option (1) : (a)-(iv), (b)-(i), (c)-(ii), (d)-(iii)
📚 Biotechnology and its Applications Easy
📋 Given Parameters & Problem Setup
Column I (Technology/Disease) (a) Bt cotton, (b) Adenosine deaminase deficiency, (c) RNAi, (d) PCR
Column II (Association) (i) Gene therapy, (ii) Cellular defence, (iii) Detection of HIV infection, (iv) Bacillus thuringiensis
⚡

The 30-Second Exam Hall Shortcut: ⚡ "Bt = Bacillus; ADA = Gene therapy; RNAi = Cellular defence; PCR = HIV detection"

⏱️ 30 seconds

Bt cotton uses Bacillus thuringiensis (a->iv). ADA deficiency was treated by the first clinical Gene therapy in 1990 (b->i). RNAi is a method of cellular defence in all eukaryotic organisms (c->ii). PCR is used for early molecular detection of HIV infection (d->iii). Match gives Option (1) in 10 seconds!

1 Bt cotton -> (iv) Bacillus thuringiensis.
2 ADA deficiency -> (i) Gene therapy (1990 four-year-old girl).
3 RNAi -> (ii) Cellular defence in all eukaryotes.
4 PCR -> (iii) Detection of HIV infection (molecular diagnostics).
5 Mapping: (a)-(iv), (b)-(i), (c)-(ii), (d)-(iii) -> Option 1.
🛡️
Why You Can 100% Trust This Shortcut: NCERT Biology · Biotechnology and its Applications (Medical & Agricultural Applications)
📐

Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Match Bt cotton

Bt cotton is an insect-resistant transgenic crop created by introducing endotoxin cry genes from the soil bacterium Bacillus thuringiensis. Thus, (a) matches (iv).

Step 2

Match Adenosine Deaminase (ADA) Deficiency

The first clinical gene therapy was given in 1990 to a 4-year-old girl with adenosine deaminase (ADA) deficiency, where functional ADA cDNA was introduced into her lymphocytes using a retroviral vector. Thus, (b) matches (i).

Step 3

Match RNA Interference (RNAi)

RNAi takes place in all eukaryotic organisms as a method of cellular defence involving silencing of a specific mRNA due to a complementary dsRNA molecule. Thus, (c) matches (ii).

Step 4

Match Polymerase Chain Reaction (PCR)

PCR is a routine molecular diagnostic technique used to detect pathogens like HIV and cancer mutations at very low concentrations even before symptoms appear. Thus, (d) matches (iii).

⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan
1 A
✓ 100% Correct
Verdict & Scientific Reason:

Accurate pairing across all four biotechnology principles and applications.

💡
Why this is airtight: None; canonical biotechnology curriculum mapping.
2 B
✗ Incorrect
Verdict & Scientific Reason:

Incorrect; Bt cotton is not used to detect HIV infection.

⚠️
Student Fallacy (Why candidates pick this trap): Swapping agricultural crops with clinical diagnostics.
3 C
✗ Incorrect
Verdict & Scientific Reason:

Incorrect; ADA deficiency is not related to HIV detection in this pairing.

⚠️
Student Fallacy (Why candidates pick this trap): Mismatching clinical conditions.
4 D
✗ Incorrect
Verdict & Scientific Reason:

Incorrect; Bt cotton is not gene therapy.

⚠️
Student Fallacy (Why candidates pick this trap): Confusing transgenic plant engineering with human gene therapy.
⚠️

NTA Trap Alert: RNAi Function vs ELISA vs PCR

RNAi = Cellular defence against viruses/transposons. PCR = Amplification & early HIV detection. ELISA = Antigen-antibody interaction detection.

🛡️ How to avoid the -1 mark: Pair the keyword directly: RNAi = "Cellular defence"; ADA = "Gene therapy"!
📖

Core NEET Syllabus Standard

Zoology · Biotechnology and its Applications Standard Benchmark
Core Scientific Principle Tested:

""

Syllabus Focus: Biotechnological Tools and Applications Match
✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

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