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Q.120 Botany ⭐ 360° Option Elimination Active
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NEET 2025 Botany Question 120 Solution

Topic: Human Health and Disease · Official NTA Booklet Code 45
NEET 2025 Botany Question 120: Cancer Detection, Imaging, and Immunotherapy vs Chemotherapy

Question

Which are correct: A. Computed tomography and magnetic resonance imaging detect cancers of internal organs. B. Chemotherapeutics drugs are used to kill non-cancerous cells. C. α-interferon activates the cancer patients' immune system and helps in destroying the tumour. D. Chemotherapeutic drugs are biological response modifiers. E. In the case of leukaemia blood cell counts are decreased. Choose the correct answer from the options given below:

✓
Verified Against NTA Final Answer Key
Option (4) : A and C only
📚 Human Health and Disease Medium
📋 Given Parameters & Problem Setup
Statement A Computed tomography and magnetic resonance imaging detect cancers of internal organs.
Statement B Chemotherapeutics drugs are used to kill non-cancerous cells.
Statement C α-interferon activate the cancer patients' immune system and helps in destroying the tumour.
Statement D Chemotherapeutic drugs are biological response modifiers.
Statement E In the case of leukaemia blood cell counts are decreased.
⚡

The 30-Second Exam Hall Shortcut: ⚡ Cancer Oncology Diagnostics Fingerprint

⏱️ Save ~35 seconds

CT and MRI scan internal organs (A is TRUE)! α-interferon is the Biological Response Modifier destroying tumours (C is TRUE)! Chemotherapy targets CANCER cells (B false)! α-interferon is BRM, not chemo (D false)! Leukaemia has INCREASED WBCs (E false)! A and C only!

1 Evaluate each statement meticulously:
2 - A: "CT and MRI are very useful to detect cancers of internal organs." -> NCERT verbatim TRUE!
3 - B: Chemotherapy is intended to kill CANCEROUS cells (side effects damage normal cells, but that is not their purpose). -> FALSE!
4 - C: "Patients are given substances called biological response modifiers such as α-interferon which activates their immune system and helps destroy the tumour." -> NCERT verbatim TRUE!
5 - D: Biological response modifiers are biological agents (e.g. α-interferon), NOT conventional cytotoxic chemotherapeutic drugs. -> FALSE!
6 - E: Leukaemia is blood cancer caused by uncontrolled proliferation of leukocytes (counts are enormously INCREASED, not decreased). -> FALSE!
7 Conclusion: Statements A and C only are correct (Option 4)!
8 Select Option (4)!
🛡️
Why You Can 100% Trust This Shortcut: Infectious Pathogens & Vector Transmission (NCERT Biology · Human Health and Disease: Plasmodium, Entamoeba, Wuchereria).
📐

Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Diagnostic Imaging in Oncology (Statement A)

Detection of cancers in internal organs (such as brain, lungs, liver, pancreas) requires non-invasive cross-sectional and high-contrast imaging:

  • • Computed tomography (CT) uses X-rays to generate a three-dimensional image of the internals of an object.
  • • Magnetic resonance imaging (MRI) uses strong magnetic fields and non-ionising radiations to accurately detect pathological and physiological changes in living tissue.
  • • NCERT states: "Computed tomography and magnetic resonance imaging are very useful to detect cancers of the internal organs." Thus, Statement A is correct.
Step 2

Chemotherapy and Its Targets (Statement B & Statement D)

Chemotherapy involves cytotoxic chemical drugs that inhibit rapid cell division:

  • • Chemotherapeutic drugs are designed specifically to kill rapidly dividing cancerous cells. Although hair loss and anaemia occur due to collateral damage to normal proliferating cells, stating they are "used to kill non-cancerous cells" is completely false. Thus, Statement B is incorrect.
  • • Statement D claims chemotherapeutic drugs are biological response modifiers. Biological response modifiers (BRMs) are immuno-stimulatory proteins (such as α\alpha-interferon) that boost the host immune surveillance, whereas chemotherapeutic drugs are small-molecule synthetic chemicals or antibiotics (e.g., cisplatin, vincristine, methotrexate). Thus, Statement D is incorrect.
Step 3

Biological Response Modifiers and α-Interferon (Statement C)

Immunotherapy in cancer treatment:

  • • Tumour cells frequently evade immune surveillance because they are self-derived.
  • • Administration of biological response modifiers such as α\alpha-interferon activates natural killer (NK) cells and cytotoxic T-lymphocytes, aiding the immune destruction of the tumour.
  • • Thus, Statement C is correct.
Step 4

Pathology of Leukaemia (Statement E)

Leukaemia is a malignant neoplasm of hematopoietic stem cells in the bone marrow characterized by abnormal, uncontrolled proliferation and massive accumulation of immature or abnormal white blood cells (leukocytes) in circulating blood. The leukocyte count is markedly elevated (often > 100,000/mm³), not decreased. Thus, Statement E is incorrect.

Step 5

Conclusion

Only Statements A and C are correct, matching Option (4).

Correct Statements=A and C only\text{Correct Statements} = A \text{ and } C \text{ only}
⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan
1 A
✗ Incorrect
Verdict & Scientific Reason:

Incorrect. Both B and D are factually and clinically false.

⚠️
Student Fallacy (Why candidates pick this trap): Thinking chemotherapeutics are aimed at non-cancerous cells or classified as BRMs.
2 B
✗ Incorrect
Verdict & Scientific Reason:

Incorrect. Both D and E are false (leukaemia increases blood cell counts, and BRMs are interferons).

⚠️
Student Fallacy (Why candidates pick this trap): Believing leukaemia causes decrease in blood cell counts.
3 C
✗ Incorrect
Verdict & Scientific Reason:

Incorrect. While C is true, D is false because chemotherapeutic drugs are not biological response modifiers.

⚠️
Student Fallacy (Why candidates pick this trap): Conflating chemical drugs with immunological response modifiers.
4 D
✓ 100% Correct
Verdict & Scientific Reason:

100% correct. CT/MRI accurately detect internal cancers (A), and α-interferon activates the patient immune system to destroy tumours (C).

💡
Why this is airtight: None; pristine knowledge of NCERT oncology.
⚠️

NTA Trap Alert: Chemotherapy Side Effects vs Therapeutic Purpose & Leukaemia Count

Two traps here: 1. Chemotherapy causes hair loss, but its purpose is killing cancer cells, not normal cells! 2. Leukaemia is a cancer of WBCs, leading to uncontrolled proliferation (INCREASE in WBC counts), not a decrease!

🛡️ How to avoid the -1 mark: Cancer = Uncontrolled proliferation = Counts INCREASE. BRMs = α-interferon, NOT chemotherapy.
📖

Core NEET Syllabus Standard

NEET Biology Core Syllabus · Human Health and Disease Standard Benchmark
Core Scientific Principle Tested:

"CT/MRI detect internal tumors; α-interferon acts as a biological response modifier to activate tumor destruction."

Syllabus Focus: Cancer · Detection and Treatment
✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗
A & C are Accurate & Clinically sound: CT/MRI detects (A), α-interferon destroys (C)!

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