Q.165 Zoology ⭐ 360° Option Elimination Active

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NEET 2025 Zoology Question 165 Solution

Topic: Chemical Coordination and Integration · Official NTA Booklet Code 45

Question

Which of the following hormones released from the pituitary is actually synthesized in the hypothalamus?

(1)Luteinizing hormone (LH)
(2)Anti-diuretic hormone (ADH)
(3)Follicle-stimulating hormone (FSH)
(4)Adenocorticotrophic hormone (ACTH)

✓

Verified Against NTA Final Answer Key

Option (2) : Anti-diuretic hormone (ADH)

📚 Chemical Coordination and Integration Easy

📋 Given Parameters & Problem Setup

Site of Release Pituitary gland (posterior pituitary / neurohypophysis)

Site of Actual Synthesis Hypothalamus (supraoptic and paraventricular nuclei)

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The 30-Second Exam Hall Shortcut: ⚡ Posterior Pituitary Synthesis Fingerprint

⏱️ Save ~15 seconds

Posterior pituitary (neurohypophysis) does NOT synthesize any hormones! It only STORES and RELEASES Oxytocin and ADH (Vasopressin), which are synthesized by the HYPOTHALAMUS! ADH is the answer!

1 Recall NCERT Section 22.2.2 (The Pituitary Gland) verbatim:

2 - "Neurohypophysis (pars nervosa) also known as posterior pituitary, stores and releases two hormones called oxytocin and vasopressin, which are actually synthesised by the hypothalamus and are transported axonally to neurohypophysis."

3 - Vasopressin is also known as Anti-diuretic hormone (ADH).

4 - LH, FSH, and ACTH are synthesized directly by cells of the anterior pituitary (pars distalis).

5 Synthesized in hypothalamus = Anti-diuretic hormone (ADH)!

6 Select Option (2) Anti-diuretic hormone (ADH)!

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Why You Can 100% Trust This Shortcut: Pituitary Hormones & Hypothalamic Axis Control (NCERT Biology · Chemical Coordination and Integration: Anterior vs Posterior neurohypophysis).

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Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Anatomical Organization of the Pituitary Gland

The pituitary gland (hypophysis cerebri) is divided into two anatomically and embryologically distinct lobes:

• Adenohypophysis (Anterior Pituitary): Originates from Rathke's pouch (oral ectoderm). Its glandular cells synthesize and secrete true trophic hormones: Growth Hormone (GH), Prolactin (PRL), Thyroid Stimulating Hormone (TSH), Adrenocorticotrophic Hormone (ACTH), Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH).
• Neurohypophysis (Posterior Pituitary / Pars Nervosa): Originates from downward neural outgrowth of the hypothalamus (infundibulum). It contains non-secretory pituicytes and axon terminals of hypothalamic neurosecretory cells.

Step 2

Synthesis in Hypothalamus and Axonal Transport

Mechanism of ADH and Oxytocin production:

• The cell bodies of neurosecretory neurons located in the supraoptic and paraventricular nuclei of the hypothalamus synthesize Oxytocin and Vasopressin (Anti-diuretic hormone / ADH).
• These peptide hormones are packaged into neurosecretory granules and transported down unmyelinated axons through the hypothalamo-hypophysial tract to nerve terminals in the neurohypophysis.
• The posterior pituitary stores and releases them into the systemic circulation upon appropriate physiological stimulation (e.g. osmoreceptor activation for ADH).
• Thus, the posterior pituitary synthesizes ZERO hormones itself; ADH is synthesized in the hypothalamus.

Step 3

Conclusion

Anti-diuretic hormone (ADH) is the pituitary-released hormone that is actually synthesized in the hypothalamus, matching Option (2).

\text{Synthesized in Hypothalamus} \xrightarrow{\text{Axonal Transport}} \text{Released by Posterior Pituitary: ADH \& Oxytocin}

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360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan

1 A

✗ Incorrect

Verdict & Scientific Reason:

Incorrect. LH is synthesized and secreted by gonadotroph cells of the anterior pituitary.

⚠️

Student Fallacy (Why candidates pick this trap): Confusing anterior pituitary gonadotropins with posterior pituitary neurohormones.

2 B

✓ 100% Correct

Verdict & Scientific Reason:

100% correct. Direct verbatim NCERT fact: ADH (vasopressin) is synthesized by hypothalamic neurons and released by neurohypophysis.

💡

Why this is airtight: None; textbook mastery.

3 C

✗ Incorrect

Verdict & Scientific Reason:

Incorrect. FSH is synthesized directly by anterior pituitary gonadotrophs under GnRH regulation.

⚠️

Student Fallacy (Why candidates pick this trap): Confusing hypothalamic releasing hormones with neurohypophysial products.

4 D

✗ Incorrect

Verdict & Scientific Reason:

Incorrect. ACTH is synthesized by corticotroph cells of the anterior pituitary.

⚠️

Student Fallacy (Why candidates pick this trap): Thinking all pituitary hormones originate in the hypothalamus.

⚠️

NTA Trap Alert: Hypothalamic Releasing Hormones vs Posterior Pituitary Hormones

The hypothalamus makes TWO kinds of hormones: 1. Releasing/Inhibiting hormones (GnRH, TRH, CRH) that travel via hypophysial portal circulation to control the ANTERIOR pituitary. 2. ADH and Oxytocin that travel axonally to be STORED and RELEASED by the POSTERIOR pituitary!

🛡️ How to avoid the -1 mark: Hormones released from posterior pituitary but made in hypothalamus = ADH and Oxytocin.

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Core NEET Syllabus Standard

NEET Biology Core Syllabus · Chemical Coordination and Integration Standard Benchmark

Core Scientific Principle Tested:

"Neurohypophysis stores and releases oxytocin and vasopressin (ADH), which are synthesized by the hypothalamus."

Syllabus Focus: The Pituitary Gland · Neurohypophysis

✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

HYPOTHALAMUS makes the PAIR: Oxytocin & ADH (Stored at Posterior Pituitary)!

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NEET 2025 Zoology Question 165 Solution

Question

The 30-Second Exam Hall Shortcut: ⚡ Posterior Pituitary Synthesis Fingerprint

Step-by-Step Rigorous Workflow & Mathematical Proof

Anatomical Organization of the Pituitary Gland

Synthesis in Hypothalamus and Axonal Transport

Conclusion

360° Option Elimination Engine Key Feature

NTA Trap Alert: Hypothalamic Releasing Hormones vs Posterior Pituitary Hormones

Core NEET Syllabus Standard

Ready to attempt under real exam pressure?

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